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Whorton Engineering Inc is a Anniston, AL-based company in the Business Services sector.
William Nycum & Associates Limited is a Halifax, NS-based company in the Business Services sector.
TIXiMED, Inc. is focused on developing and commercializing TXNIP inhibiting medication as a first-of-its-kind oral therapeutic for Type 1 and Type 2 diabetes. TIXiMED is the exclusive license holder for the patent (composition of matter and method of use) surrounding TIX100, a novel small molecule that normalizes pancreatic beta cell TXNIP, a detrimental protein elevated in Type 1 and Type 2 diabetes. Increased TXNIP causes pancreatic islet dysfunction and death of insulin-producing beta cells and thereby contributes to the development and progression of diabetes. Diabetes affects more than half a billion people worldwide. Those affected by Type 1 diabetes are dependent on multiple daily insulin injections or continuous insulin infusions to stay alive and manage their blood sugar. Oral anti-diabetic drugs are only approved for Type 2 diabetes, but can be associated with multiple side effects, underlining the need for novel and better oral diabetes medications for Type 1 and Type 2 diabetes. TXNIP inhibition has recently been demonstrated to be an effective and safe therapeutic approach in adults and children with recent onset Type 1 diabetes and TIX100 shows beneficial, anti-diabetic effects in 4 different mouse models. Advantages of TIX100 include oral availability, no associated hypoglycemia or weight gain, potent inhibition of detrimental TXNIP in human islets, and a favorable pharmacokinetic and safety profile. In addition, TIX100 inhibits excessive glucagon secretion and hepatic glucose production and protects against fatty liver. Thus, TIX100 holds promise for durable, weight-neutral improvement in glycemic control in Type 1 and Type 2 diabetes by targeting common underlying pathology and promoting patients own islet cell health.
Our firm offers a full range of professional tax, audit, accounting, and consulting services. Advising with Vision® is more than just a tagline, it is how we do business. We understand the importance of our role as CPAs and advisors and the trust you place in us. We take a proactive approach and work with you to seek out business opportunities. We help you maintain a competitive advantage and are dedicated to assisting you throughout each phase of the business life cycle. Our clients success has been key to our success. We provide high-touch service to the clients we serve, both at the corporate and owner levels. We have a strong entrepreneurial spirit and we know firsthand the challenges and opportunities of being a business owner. We understand the need for management to constantly look to the future in todays ever-changing business environment. Our experience is not based solely upon case studies and textbook solutions, but also upon actual business experience.
Isp, Inc. is a Silverdale, WA-based company in the Business Services sector.